Beta Blocker in Case of Heart Failure Essay

Introduction Beta- blockers, also known as genus Beta antagonists, beta-adrenergic blocking agents, or beta-adrenergic antagonists, are drugs that are prescribed to speak several different types of conditions, including hypertension (high blood pressure), angina, some defective internality rhythms, heart attack (myocardial infarction), anxiety, migraine, glaucoma, and overactive thyroid symptoms.Beta-blockers block the action of the sympathetic nervous brass of the heart, thus reducing stress on the heart. The sympathetic nervous dust activates the fight or flight response. It is part of the autonomic nervous system.Beta-blockers block beta-adrenergic substances, such as apinephrine (adrenaline) in the autonomic nervous system (involuntary nervous system). They slow down the heart flash, decrease the force of the contractions of the heart muscles, and boil down blood watercraft contraction in the heart, brain, as well as the rest of the body.Generic Names Carvedilol / Metopr olol / atenolol / Bisprolol / Propranolol / Timolol Brand Names Coreg / Lopressor, Toprol XL / Tenormin / Zebeta / Inderal / Blocadren How it is given Oral (tablet or capsule), intravenous (IV)Indications Doctors whitethorn prescribe beta-blockers for long-sufferings with tachycardias (rapid heart rates). They help patients with angina by lowering the amount of atomic number 8 the heart muscles require. Angina pectoris occurs when the heart requires more oxygen than it is getting.Beta-blockers can help hypertensive patients because their effect on blood vessels lower blood pressure.Patients with hereditary tremors as well as those who suffer from migraines may pull ahead from taking beta-blockers.In other words, beta-blockers are known as beta- adrenoreceptor blocking agents and are used to treat Commonly* Angina* Heart loser* High blood pressure (hypertension)* Irregular heart beat (atrial fibrillation)* Myocardial infarction (heart attack) less commonly* Prevention of migrain e* Thyrotoxicosis (overactive thyroid)* Anxiety* Tremor* Glaucoma (as inwardness drops)-The first clinic anyy useful beta adrenergic receptor antagonist was called Propranolol. It was invented by Sir James W. gruesome (born 1924), a Scottish doctor and pharmacologist. Sir James also synthesized Cimetidine (for the preaching of heartburn and peptic ulcers) and was awarded the Nobel sugar for Medicine in 1988. Propranolol revolutionized the medical management of angina pectoris it is considered as one of the major contri hardlyions to clinical medication and pharmacology of the 20th century. Mechanism of work The use of beta blockers in heart failure is originally associated with the medications effect on heart rate. The medication, by way of the sympathetic nervous system, decreases the patients heart rate, preventing the heart from having to work harder because of the condition. This effect was not considered desirable for heart failure patients when the medication was first studied, however.A lowered heart rate has the risk of worsening heart failure symptoms, but as research continued, beta blockers proved to have benefits that outweighed this risk. The exact etiology of the case of heart failure is of importance when a doctor is deciding whether to use beta blockers. A case that is present because of stricken ventricular filling, in contrast to a case caused by impaired ventricular emptying, seems to respond fail to beta blockers in heart failure.In addition to their sympathetic action on heart muscle, beta blockers in heart failure influence the kidneys renin/angiotensin system. Beta blocking medications cause the secernment of the hormone, renin, to decrease. As renin decreases, a cascade of events transpires that decrease the hearts demand for oxygen. The cascade lowers extracellular tranquil volume and increases the bloods ability to hold and carry oxygen to body tissues. Beta blocker treatment can be supplemented, and is supplemented in mos t cases, with diuretics and angiotensin-converting enzyme (ACE) inhibitors that enhance this effect.Patients who have significant dyspnea brusqueness of breath while they remain at rest are among those who may not be candidates for treatment with beta blockers. Having severe dyspnea can increase the risks that are associated with beta blocker treatment. Some patients are considered hemodynamically unstable if their blood does not carry oxygen well, even under normal circumstances these patients may not be good candidates for treatment either.Heart problems for a patient with heart problems beta-blockers can reduce the workload for the heart so that it does not have to work so hard to supply all parts of the body with oxygen-rich blood. For people with angina, heart failure, or after a heart attack, reducing the hearts workload is crucial.Drugs Used in case of Heart Failure * Propranolol* Metoprolol tartrate (Lopressor) and metoprolol succinate (Toprol XL) * * Carvedilol (Coreg) * * Bucindolol (Bextra) * * Bisoprolol (Zebeta) * spatial relation Effects The most common side effects are* Cold feet* Cold hands* play* Fatigue* Nausea* Very slow heartbeatThe following less common side effects are also possible* Sleeping difficulties and disturbances* Bad dreams (nightmares)* Erectile dysfunction (male inability to achieve or sustain an erection during sex)References Myo clinicwww.Hearthealthywomen.comhttp//www.wisegeek.com